AIM: To investigate the effect of heparin treatment on capsular tension ring(CTR)in the prevention of after-cataract postoperative patients with Marfan syndrome and subluxation of lens.

METHODS: Totally 34 cases(56 eyes)were divided randomly into experimental and control groups. Preoperative heparin 12500 units was added to 500mL Ringer's infusion, and CTR was dealt with heparin stock solution soak for 20 minutes in experimental group; there was no any drugs in the control group's solution, and CTR was not dealt with heparin. Postoperative IOP, anterior chamber reaction, corneal edema, IOL position, posterior capsular opacification were observed.

RESULTS: There was statistically significant difference in the posterior capsular opacification between the heparin group(13.3%)and the contral group no-heparin(69.2%)(P<0.01). In addition, anterior chamber reaction of the experimental group was significantly lighter than the control group. However, no significant differences were found between the two groups in IOP and corneal edema.

CONCLUSION: The present results indicate that there is the preventive effect on posterior capsular opacification by CTR soaked in heparin in postoperative patients with Marfan syndrome and subluxation of lens, thus contributing to the recovery of visual function.