Cui-Wei Zhang
Department of Ophthalmology, Specialists Outpatient Department, Shenzhen Healthcare Office, Shenzhen 518002, Guangdong Province, ChinaJin-Song Mo
Shenzhen Eye Hospital, Shenzhen 518040, Guangdong Province, ChinaXu-Yang Liu
Shenzhen Eye Hospital, Shenzhen 518040, Guangdong Province, ChinaQing-Shan Chen
Shenzhen Eye Hospital, Shenzhen 518040, Guangdong Province, ChinaAIM: To observe and analyze on the incidence rate and causes of complications after anintravitreal injection of bevacizumab.
METHODS: Totally, 207 cases(207 eyes)with wet age-related macular degeneration were selected randomly. All cases were treated with intravitreal injections of bevacizumab(1.5mg/0.06mL)and asked for chief complaints at 1 day, 1 week, 4, 12 weeks after operation, and also examined for routine visual acuity(best corrected visual acuity, BCVA), non-contact tonometer, slit lamp microscope and indirect ophthalmoscope etc.
RESULTS: Among 207 cases(207 eyes), visual acuity improved efficiency was 90.8% 12 weeks after treatment, foreign body sensation was found in 7 cases(3.4%), eyelid skin pruritus in 1 case(0.5%), conjunctival congestion in 6 cases(2.9%), subconjunctival hemorrhage in 1 case(0.5%), post-operative intraocular pressure elevation in 2 cases(1.0%).
CONCLUSION: The intravitreal injection of bevacizumab is effective with fewer complications. We propose to carry out a further randomized multicenter and larger-sample clinical research and further draw up the clinical application criterion of bevacizumab.
Cui-Wei Zhang, Jin-Song Mo, Xu-Yang Liu,/et al.Analysis on complications after intravitreal injection of bevacizumab. Guoji Yanke Zazhi( Int Eye Sci) 2013;13(8):1654-1656
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