AIM: To compare the efficacy of 577nm micro-pulse laser and drug in the treatment of central serous chorioretinopathy(CSC).

METHODS: Forty-five CSC cases(45 eyes), in our hospital from January 1, 2012 to September 31, 2012, were received 577nm micro-pulse laser in laser group. Forty cases(40 eyes)got drug in drug group. The efficacy of two groups was compared.

RESULTS: All eyes in laser group were cured at 6 weeks after treatment, which was shorter than that in drug group.

CONCLUSION: 577nm micro-pulse laser treatment for CSC is safe and effective, and can reduce the recurrence of CSC.