Ultrastructural changes of retinal pigment epithelium-photoreceptor complex in early aging rats

doi:10.3980/j.issn.1672-5123.2014.02.10

Home > Archive>Volume 14, Issue 2, 2014 >236-238. DOI:10.3980/j.issn.1672-5123.2014.02.10

Ultrastructural changes of retinal pigment epithelium-photoreceptor complex in early aging rats
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                        10.3980/j.issn.1672-5123.2014.02.10
                    
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Fund Project:Key Discipline of College of Optometry of China Medical University, China; Special Project of Beijing Health Development and Scientific Research, China(No.2011-1001-02); Natural Science Foundation of Beijing, China(No.7132044)

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Abstract:

AIM:To observe the ultrastructural changes of retinal pigment epithelium(RPE)-photoreceptor complex in early aging rats.

METHODS: Retinas of 3-month old and 12-month old rats were prepared into semi-thin sections and then observed under transmission electron microscope to evaluate the changes of RPE-photoreceptor complex.

RESULTS: Apoptosis of RPE cells and degenerative changes of RPE-photoreceptor complex were found in retinas of 12-month old rats.

CONCLUSION: RPE-photoreceptor complex degeneration is an early manifestation of the retinal aging.

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Zhen Li, Jie Li, Rong Wang, et al. Ultrastructural changes of retinal pigment epithelium-photoreceptor complex in early aging rats. Guoji Yanke Zazhi( Int Eye Sci) 2014;14(2):236-238

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Publication History

Received:September 26,2013
Revised:December 31,2013
Adopted:
Online: January 20,2014
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