AIM: To observe the effect of the wavefront aberration-guided combining Q-value optimized LASEK(WG-QO-LASEK).

METHODS: Retrospective analyzed the pre- and post-operative clinical data of 140 cases(280 eyes)that had gone through WG-QO-LASEK in the department of ophthalmology in our hospital. The observational index was compared in patients' visual acuity of pre- and post-operative and the subjective and objective examination of vision.

RESULTS: There were no severe postoperative complications. Totally 132 patients'(264 eyes)uncorrected visual acuity(UCVA)was achieved to the expected correction degree within ±0.5D. Best corrected visual acuity(BCVA)improved one line in 88 eyes(31.4%)and 2 lines in 46 eyes(16.4%). Postoperative scores of NEI-RQL-42 were significantly higher than preoperative ones. After operation, the proportion of higher-order aberrations increased, mainly manifested in spherical aberration and coma, but it did not influence the visual quality obviously.

CONCLUSION: WG-QO-LASEK treatment of myopia has good predictability, accuracy and safety.