Age-related macular degeneration(AMD)is the leading cause of irreversible visual loss in elderly people among white-dominated population. At percent, treatment for AMD includes anti-vascular endothelial growth factor antibody(Anti-VEGF)drug treatment, photodynamic therapy(PDT), topical application of triamcinolone acetonide(TA)and laser therapy(nanosecond laser)etc. Through comparative analysis of different treatment methods of AMD, we review the mechanism, clinical efficacy, adverse events and cost effectiveness to provide the basis for clinical treatment.