AIM: To explore the clinical therapeutic effect of compound Xueshuantong combined with laser treatment in central serous chorioretinopathy(CSCR)patients.

METHODS: A total of 181 cases of central serous chorioretinopathy patients treated in our hospital were randomly divided into treatment group(91 cases)and control group(90 cases). The patients in control group underwent laser treatment, those in treatment group received oral compound Xueshuantong after laser treatment. Clinical curative effect, the average light sensitivity and serum testosterone, estrogen levels of two group were compared.

RESULTS: After 3wk of treatment, the total effective rate of the treatment group was 90.1%, 72.2% in the control group, the treatment group was significantly higher(χ²=10.473, P=0.001); After 6wk of treatment group, the total effective rate was also significantly higher than that in the control group(χ²=4.499, P=0.034). Healing time, visual recovery time in treatment group was significantly less than those in the control group, the mean sensitivity was significantly higher, the difference between the two groups was statistical significance(P<0.05). After the treatment the hormone of patients in the two groups were significantly decreased, the treatment to reduce the level of serum hormone level was significantly better than those in the control group, the difference between the two groups was statistical significance(P<0.05).

CONCLUSION: Compound Xueshuantong combined with laser in the treatment of central serous chorioretinopathy, can significantly improve the efficacy, shorten the course of disease, is conducive to the recovery of visual function, and worth the clinical promotion.