AIM:To understand the clinical effect of trabeculectomy with mitomycin and interferon therapy on neovascular glaucoma.

METHODS:Neovascular glaucoma patients in our hospital from January 2011 to January 2013 were sampled, from them, 57 cases(57 eyes)were randomly divided into two groups, control group received routine trabeculectomy for treatment, the experimental group accepted combination therapy of trabeculectomy + mitomycin + interferon. The clinical efficacy of two groups were observed.

RESULTS:The total effective rate(96%)in experimental group was significantly better than that in the control group(76%), and the visual acuity, filtering bleb and postoperative 1wk, 1a of intraocular pressure changes were better than those of the control group, there was a statistically significant difference(P<0.05). The rate of complications in experimental group(10%)was slightly higher than that of the control group(7%), but there was no statistically significant difference(P>0.05).

CONCLUSION:Trabeculectomy combined mitomycin and interferon treatment of neovascular glaucoma has exact clinical effect, and is worthy of clinical popularization and application.