AIM:To investigate the factors and solutions of Tibetan Plateau excimer laser in situ keratomileusis(LASIK)for myopia overcorrection.

METHODS: The relevant information, 32 cases(58 eyes)in 126 cases(252 eyes)had obvious overcorrection after LASIK were analyzed.

RESULTS: Two months after surgery, 32 cases(58 eyes)overcorrection(23.0%), uncorrected visual acuity of 0.5～0.8, overcorrection range of +1.50 ～ +2.25DS, subjective inserts were ≥1.0; Five case(7 eyes)overcorrection 6mo after surgery(2.8%), uncorrected visual acuity 0.8～1.0^-2, overcorrection range is +0.75 ～ +1.25DS, subjective inserts were ≥1.0. Corneal thickness of overcorrection was 500～563μm, preoperative refraction was -5.00 ～ -7.50D, astigmatism -1.50 ～ -2.75DC, preoperative best corrected visual acuity ≥1.0.

CONCLUSION: Overcorrection and long recovery time after LASIK in Tibet, possibly with local factors altitude, temperature, humidity, surgical parameters and situation.