AIM: To research the clinical curative effect of Xueshuantong combined with calcium dobesilate on visual field defect caused by diabetic retinopathy.

METHODS: Sixty-four cases with diabetic retinopathy treated in our hospital patients were selected as the research objects. They were randomly divided into observation group and control group. The control group was treated with Xueshuantong, and the observation group was treated with combined treatment of calcium dobesilate. After 5mo, the clinical efficacy was compared between the two groups of diabetic retinopathy, and before and after treatment fundus photography, fluorescein angiography and visual field changes, observation of patients with adverse reactions and recurrence were performed.

RESULTS: The condition of patients was improved, and the effective rate of treatment group was 97%, and higher than that of the control group 78%, the differences were statistically significant(P<0.05); the patients in the observation group were significantly reduced bleeding spot, before and after treatment were significant difference, with statistical significance(P<0.05), field of vision gray, hemorrhage spots, and hemangioma changes in obsenartion group were significantly better than that of the control group, with statistical significance(P<0.05). In observation group, patients had no adverse reaction, and the recurrence rate was significantly less than the control group, and the recurrence rate were significant difference(P<0.05).

CONCLUSION: The patients with diabetic retinopathy treated with Xueshuantong combined with calcium dobesilate achieve satisfactory effect, and it can effectively reduce the recurrence rate and the adverse reactions, and improve the clinical symptoms. It would be widely applied in clinical practice.