AIM:To explore and study the effect of cover adjustment on binocular visual function in children with anisometropic amblyopia.

METHODS: Forty-five children with anisometropic amblyopia of our hospital from July 2014 to April 2015 were as the study group, and treated by cover adjustment. Then 40 cases of healthy volunteers were selected as the blank control group. The binocular visual function of the subjects was observed.

RESULTS: Before treatments, at 1 and 3mo after treatments, the positive rates of binocular fusion were respectively 62%, 76% and 87%, which at 3mo after treatments was significantly higher than that before treatments(P <0.05). But the difference between that Before treatments and 1mo after treatments was not significant(P>0.05). Before treatments, at 1 and 3mo after treatments the numbers of children whose stereo visions were 3000 "～801" were respectively 26,13 and 2, and the numbers of children whose stereo visions were 800 "～401" were respectively 12,13 and 6; the numbers of children whose stereo visions were 400 "～101" were respectively 7,15 and 25; the numbers of children whose stereo visions were≤100" were respectively 0,4 and 12. Far apart from the point of rupture and the convergence function in the study group after treatments were improved and significantly higher than those in the control group(both P<0.05); the rupture points, fuzzy points of close out and convergence function were significantly higher than those before treatments(all P<0.05). The rupture points, fuzzy points of part out were higher than those of control group, while the convergence function was lower(all P<0.05).After treatments, the amplitude and sensitivity of both eyes in the study group were significantly higher than those before treatments(all P<0.01); the amplitude of both eyes was significantly lower than that in the control group P<0.01, and the sensitivity of both eyes had no difference with that in the control group(P>0.05). After cover adjustment treatment, the lag of binocular regulation significantly decreased than that before treatments(P <0.05), but there was no significant difference between the two groups(P>0.05). In the study group(45 cases with 90 eyes)52 eyes were cured, 24 eyes improved, 14 eyes ineffective; the total effective rate was 84%.

CONCLUSION: Cover adjustment has some improvement effect on binocular visual function in children with anisometropic amblyopia.