AIM:To study the refraction status in 354 amblyopia children and to investigate the related influence factors for the treatment effect.

METHODS:Three hundred and fifty-four children diagnosed as ametropia amblyopia from January 2010 to June 2015 in our hospital were selected. The children were divided into groups according to the children's age, refraction types of amblyopia and degree of amblyopia. The clinical treatment effect of different groups was compared.

RESULTS:The cure rate for amblyopia children in different groups was significantly different(P<0.05); as the ages of children increasing, the cure rate was gradually reduced. The cure rate for children with different amblyopia types was not totally the same. The cure rate of different groups was sorted from low to high:myopia groupP<0.05); the clinical efficacy for children with different amblyopia degrees was significantly different(P<0.05). As the amblyopia degrees increasing, the cure rate was also constantly declined.

CONCLUSION:The treatment effect of ametropia amblyopia is correlated with the children's age, types of amblyopia and degree of amblyopia. It has a poor treatment effect for the older children with severe myopia and amblyopia.