AIM: To evaluate the effect for refractory glaucoma by using Ex-Press miniature implantation with deep sclerectomy.

METHODS: Thirty eyes in 24 patients with refractory glaucoma were treated by Ex-Press miniature(P50)implantation with deep sclerectomy. The patients' symptom, intraocular pressure(IOP), visual acuity and complications were analyzed in a 12mo follow-up period.

RESULTS: During the follow-up period, all patients' ocular pain was reduced. The mean IOP before operation and at the last follow-up time were 51.15±2.60mmHg(1kPa=7.5mmHg)and 15.11±2.51mmHg, respectively, there was significant difference(P<0.05). Postoperative visual acuity was improved in 8 eyes,had no significant change in 22 eyes. After operation, hyphema of anterior chamber appeared in 2 eye(7%), which were obsorbed after 1wk.

CONCLUSION: Ex-Press miniature implantation combined with deep sclerectomy surgery is a relatively effective and safe treatment for the patients with refractory glaucoma. This method can significantly degrade the IOP, lessen ocular pain and reduce the complications risk.