AIM: To investigate hemodynamic alterations of retrobulbar vessels in proliferative diabetic retinopathy(PDR)patients with anterior segment neovascularization, before and 3mo after vitrectomy combined with panretinal photocoagulation and to explore the clinical significance.

METHODS: Color Doppler flow imaging(CDFI)was used for measurement of blood flow velocities and resistive indexes(RI)of the ophthalmic artery(OA), short posterior ciliary arteries(sPCA)and central retinal artery(CRA)in 21 eyes of 21 PDR patients with anterior segment neovascularization. CDFI parameters were obtained before and 3mo after vitrectomy combined with panretinal photocoagulation(PRP).

RESULTS: Peak systolic velocity(PSV)and end diastolic velocity(EVD)of CRA were significantly increased after surgeries, RI were decreased significantly(P<0.05). Parameters of sPCA and OA have no change after surgeries(P>0.05).

CONCLUSION: Vitrectomy combined with panretinal photocoagulation might increase the velocity of CRA, decrease RI and improve ocular blood supply postoperatively. It may delay or prevent the process of neovascular glaucoma.