AIM: To investigate the significance of optical coherence tomography(OCT)and fundus fluorescein angiography(FFA)in patients with high myopia macular degeneration.

METHODS:A total of 62 cases(104 eyes)of high myopia macular degeneration patients with OCT and FFA data from Department of Ophthalmology in Jan. 2014 to Sep. 2015 were retrospectively analyzed.

RESULTS: Highly myopic macular degeneration patients with FFA type, OCT classification had significant correlation(r=0.599, P<0.001). Type of OCT in patients with high myopia macular degeneration, with BCVA, diopter, axial length, the thickness at the central fovea measured value difference has statistically significant(P<0.05). The higher OCT classification, the lower BCVA, the smaller center of foveal thickness and diopter value and the longer axial length in patients. In degrees of myopia macular degeneration patients with FFA type, the patients with BCVA, diopter, eye axis length determination of value differences were statistically significant(P<0.05). Foveal thickness difference of no statistically significant(P>0.05). The higher FFA type, the smaller ametropia degree, BCVA values, the longer ocular axial length. FFA type patients with foveal thickness determination values were not statistically significant(P>0.05).

CONCLUSION: High myopic macular degeneration patients with OCT and FFA results have a certain degree of correlation. However, it's benefit to combine both of them for further diagnosed and treatment of patients.