AIM: To investigate the diagnostic value of Application of optical coherence tomography(OCT)angiography for early primary open angle glaucoma(POAG).

METHODS: Thirty-one eyes of 31 cases with early POAG were detected by OCT angiography. The split-spectrum amplitude-decorrelation angiography(SSADA)algorithm was used to compute optic disc angiography. The vessel density of capillaries and caliber of large vessels around the optic disc were analyzed for the correlation with nerve fiber layer(NFL)thickness and mean defect of visual field.

RESULTS: The vessel density of capillaries was 7.34±1.40 in superior and 7.76±1.34 in inferior, which showed a significant linear correlation with the NFL thickness(P<0.05). The caliber of large vessels was 94.71±11.20μm, which had a linear correlation with the mean defect of visual field.(P<0.05).

CONCLUSION: OCT angiography is a convenient technology to non-invasively measure optic disc perfusion and may be useful in the early diagnosis of primary open angle glaucoma.