AIM: To investigate the efficacy and safety of the treatment of exfoliation syndrome combined with cataract(XFSC).

METHODS: A retrospective analysis of XFSC in 130 patients(140 eyes)from January 2012 to March 2016.All patients received surgical treatment. Observation of patients with intraoperative complications, postoperative complications, postoperative visual acuity, occur of suspensory ligament abnormalities were taken.

RESULTS: The small pupil, shallow anterior chamber, anterior chamber too deep, and other complications appeared during the operations. Postoperative corneal edema, persistent corneal edema decompensation, posterior synechia, cystoid macular edema, capsular shrinkage and other complications appeared. There were 11 eyes of abnormal suspensory ligament before operation, and there were about 27 eyes with this during operations. All the 130 patients were followed up after surgery, the visual acuity when the patients left our hospital and visual acuity of the patients at 6mo after operation were improved compared with the preoperative visual acuity(P<0.05). Postoperative follow-up showed that the visual acuity of 5 eyes were light perception to 0.02, 15 eyes were 0.03-0.1, 27 eyes were 0.12-0.3, 83 eyes were 0.4-0.6, 10 eyes were ≥0.8 at 6 mo after operation. IOL was at normal position in 129 eyes, different degree of deviation in 6 eyes, 5 eyes of dislocation; capsular contraction in 17 eyes; capsular tension ring(CTR)in 32 eyes were at the normal position, 3 eyes with CTR decentration. There were 120 eyes were cured, 15 eyes better, 5 eyes ineffective.

CONCLUSION: XFSC surgery is difficult, perfect preoperative examination and reasonable and effective method of treatment can reduce the incidence of complications, beneficial to the recovery of postoperative visual function.