AIM: To evaluate the application and effect of bandage contact lens in pterygium excision combined with conjunctival transplantation(CAT).

METHODS: In a prospective, randomized, controlled clinical study, 110 patients(110 eyes)diagnosed with primary pterygium were collected in PLA NO.474 Hospital from January 2015 to January 2016. The 110 patients enrolled in the study in turn, and divided into two groups by the odd and even number. The odd number divided into bandage contact lens group(CAT + bandage contact lens, n=55), while the even number divided into control group(CAT, n=55). Visual analog scale(VAS)and corneal irritation were evaluated on 1, 3 and 7d after operation. Cornea fluorescent staining testing was carried out on 3d after operation. Following-up all the patients with 1a at least observed the recurrence of pterygium.

RESULTS:The score of VAS in bandage contact lens group less than that in control group on 1d(4.13±2.06 vs 5.80±1.93, t=4.391, P<0.001)and 3d(2.09±1.36 vs 3.65±1.65, t=5.422, P<0.001)after operation, while there was no significant difference between two groups on 7d(t=1.295, P=0.198)after operation. The corneal irritation in bandage contact lens group less than that in control group on 1d and 3d after operation(P<0.05), while there was no significant difference between two groups on 7d after operation(P=0.052). Cornea fluorescent staining testing area in bandage contact lens group was less than that in control group on 7d after operation(0.33±0.37mm² vs 2.73±2.21mm², t=7.921, P<0.01). There was no significant difference in recurrence rate between two groups after 1a operation(P=1.000).

CONCLUSION:Bandage contact lens could significantly release pain and corneal irritation, promote the healing of the corneal epitheliums in the defected area, and increase the postoperative comfort level in patients after operation.