AIM: To observe the tear film and corneal endothelial cell density in cataract patients with high myopia.

METHODS: From January 2016 to December 2016,38 cases(38 eyes)with high myopia and cataract were selected as study group, 24 males(24 eyes)and 14 females(14 eyes), average 65.2±2.37(60-72)years old. Age-related cataract patients without high myopia were as control group, 22 males(22 eyes)and 16 females(16 eyes), average 64.4±2.43(61-70)years old. The tear film and corneal endothelial cell density of the two groups were observed at 3, 7, 14d and 1mo after operations.

RESULTS: Between the two groups of preoperative SⅠt, BUT, FL, subjective rating, corneal endothelial cell density comparison, there were no statistically significant difference(P>0.05). In the two groups at 3, 7, 14d and 1mo after operations, BUT, FL, corneal endothelial cell density, subjective score comparison, the difference had statistical significance(P<0.01). Two groups after 3, 7, 14d comparative differences of SⅠt were statistically significant(P<0.01), not statistical significant at postoperative 1mo(P>0.05). At postoperative 3, 7, 14d, 1mo, FL, subjective rating, corneal endothelial cell density of the two groups were compared with preoperative, the difference was statistically significant(P<0.01).In the two groups at 3, 7, 14d after operation, SⅠt compared with the same group preoperative difference was statistically significant(P<0.01), no statistical significance when postoperative 1mo compared with preoperative(P>0.05). BUT of high myopia patients with age-related cataract surgery, at 3, 7, 14d and 1mo after operations decreased than preoperative, the difference was statistically significant(P<0.01). Age-related cataract patients without high myopia at 3, 7, 14d after operation decreased than preoperative, the difference was statistically significant(P<0.01), there was no statistically significant difference between preoperative and postoperative 1mo(P>0.05).

CONCLUSION: Phacoemulsification cataract surgery in the treatment of high myopia cataract patients is safe and reliable, and less influence on tear film and corneal endothelial cell density.