AIM: To assess the effect of press-on prisms in patients with acute-onset comitant esotropia and diplopia, focusing primarily on vision-related quality of life and binocular vision.

METHODS: Retrospective case-series study. Totally 16 acute-onset comitant esotropia patients with diplopia who received treatment in the Huzhou Central Hospital were included in this study from March 2014 to March 2017. Vision-related quality of life before press-on prism correction and 1mo after press-on prism correction were performed with the Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire(CHI-NEI-VFQ-25). In each time of follow-up, we made a minute examination, includes worth four dot test and stereo tests. Data was statistically analyzed with paired sample t test, Chi-square test and Fisher's exact test.

RESULTS: Except the degree of eye pain, color vision and perimetry, the indicators from CHI-NEI-VFQ-25 table including general health status, overall vision, mental health, social role difficulties, social functional, near activities, distant activities, independency and driving of acute-onset comitant esotropia patients with diplopia were obviously significant improved 1mo after press-on prism correction(P<0.05). One month after press-on prism correction, the fusion function and stereo acuity were significant enhanced(P<0.05).

CONCLUSION: Press-on prism correction may be helpful for binocular vision recovery in acute-onset comitant esotropia patients with diplopia, so as improve the vision-related quality of life.