Research progress of epithelial-mesenchymal transformation in posterior subcapsular opacity
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National Natural Science Foundation of China(No.81870644)

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    Abstract:

    Cataract is the first blinding eye disease in China and the main cause of blindness in most countries in the world. Currently, surgery operation is the only effective treatment. Posterior capsular opacification(PCO)is a common complication after cataract surgery, and it is also the crucial induction of vision decline. Studies have shown that epithelial-mesenchymal transition(EMT)of lens epithelial cells(LECs)remaining after surgery plays an important role in the occurrence and development of PCO. This article mainly summarizes the research progress of EMT in PCO in recent years.

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Tong Yu, Jing Wang, Jin-Song Zhang. Research progress of epithelial-mesenchymal transformation in posterior subcapsular opacity. Guoji Yanke Zazhi( Int Eye Sci) 2019;19(8):1309-1312

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Publication History
  • Received:December 21,2018
  • Revised:July 02,2019
  • Adopted:
  • Online: July 25,2019
  • Published: