Home > Archive>Volume 19, Issue 12, 2019 >2041-2044. DOI:10.3980/j.issn.1672-5123.2019.12.09
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Function of planar cell polarity in lens development
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National Natural Science Foundation of China(No.81770905)

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    Abstract:

    Regarded as a complex biological process, lens development involves a range of signal molecules and their crosstalk networks. Recently,the role of planar cell polarity(PCP)signaling pathway in lens development has attracted increasing attention. It has been reported that PCP is critical for lens morphology and transparency maintaining. The studies performed on PCP serve to provide guidelines on how to optimize the morphology of regenerated lens. This is thought as presenting an effective therapy for infant cataract from a clinical perspective. This article will give a comprehensive review of the role of PCP signaling pathways in the lens development.

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Yi-Jia Chen, Jin-Yan Li, Shuai Ouyang,/et al.Function of planar cell polarity in lens development. Guoji Yanke Zazhi( Int Eye Sci) 2019;19(12):2041-2044

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Publication History
  • Received:March 22,2019
  • Revised:October 31,2019
  • Online: November 21,2019
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