AIM: To explore the risk factors of high intraocular pressure after vitrectomy.

METHODS: Patients who underwent vitrectomy in our hospital from June 2016 to December 2018 were retrospectively analyzed, general information of patients, intraocular pressure before and after operation and relevant information of operation were recorded, Univariate and Logistic multivariate regression analysis were performed to analyze the risk factors of high intraocular pressure after vitrectomy.

RESULTS: Early high intraocular pressure occurred in 49 of 159 eyes(30.8%). Gender and age had no significant effect on the occurrence of high intraocular pressure after vitrectomy(P=0.699; P=0.416). Early high intraocular pressure after vitrectomy was closely correlated with silicone oil filling, combined cataract surgery, total retinal laser photocoagulation and vitreous hemorrhage after vitrectomy, with statistically significant differences(P<0.05). Logistic regression analysis showed that silicone oil filling, combined cataract surgery, total retinal photocoagulation and postoperative vitreous hemorrhage were independent risk factors affecting the occurrence of early postoperative high intraocular pressure(P<0.05).

CONCLUSION: Early high intraocular pressure after vitrectomy is the result of multiple factors, which is closely related to silicone oil filling, combined cataract surgery, total retinal photocoagulation and vitreous hemorrhage after vitrectomy.