Research progress of ophthalmic examination in the diagnosis of Alzheimer's disease
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Science and Technology Committee Project Supported by Chongqing(No.cstc2015jcsf10012-2)

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    Abstract:

    Alzheimer's disease(AD)is a neurological degenerative disease that is insidious onset. The main pathological features are deposition of amyloid β(Aβ)and intracellular hyperphosphorylated tau protein. In recent years, studies have found that the manifestations of AD exist not only in the brain but also in the eyes, such as impaired visual function, changes in the pupil, Aβ deposition in the lens, changes in the retina and choroid, and so on. These ocular manifestations provide clues to the early diagnosis of AD and have positive clinical and social significance. Therefore, this article reviews the ocular manifestations of AD and their use as biomarkers for diagnosis and progression.

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Han-Yun Wu, Li Zhang. Research progress of ophthalmic examination in the diagnosis of Alzheimer's disease. Guoji Yanke Zazhi( Int Eye Sci) 2020;20(6):1007-1010

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Publication History
  • Received:September 24,2019
  • Revised:May 08,2020
  • Adopted:
  • Online: May 25,2020
  • Published: