Research progress on effect of IL-17 in ocular diseases
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  • Lan Wang

    Lan Wang

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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  • Yan Li

    Yan Li

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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  • Zi-Wen Sun

    Zi-Wen Sun

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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  • Zhu-Lin Hu

    Zhu-Lin Hu

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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Fund Project:

Yunnan Province Basic Research Program(No.2018FE001-265); Innovation Found Program of Kunming Medical University(No.2020S226)

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    Abstract:

    Interleukin-17(IL-17)is an important pro-inflammatory factor in autoimmune diseases and many inflammatory diseases. Studies have shown IL-17 plays a vital role in the pathogenesis of eye disease. This paper reviews the function and mechanism of IL-17 in keratitis, dry eye, uveitis, diabetic retinopathy, and age-related macular degeneration, providing new ideas and targets for the treatment of these diseases.

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Lan Wang, Yan Li, Zi-Wen Sun,/et al.Research progress on effect of IL-17 in ocular diseases. Guoji Yanke Zazhi( Int Eye Sci) 2021;21(8):1412-1416

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Publication History
  • Received:November 19,2020
  • Revised:July 02,2021
  • Online: July 21,2021