Research progress on optical coherence tomography imaging indicators of macular edema secondary to retinal vein occlusion
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Natural Science Foundation of China(No.81603666); Capital Key Research and Development Projects of Applied Research on Clinical Characteristics(No.Z181100001718183); Research and Development Project of “Predominant Disease-Hospital Preparation-New Drug” in China Academy of Chinese Medical Sciences(No.ZZ15-XY-PT-09); In-Hospital Project of Eye Hospital of Chinese Academy of Chinese Medical Sciences(No.202021)

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    Abstract:

    Retinal vein occlusion(RVO)is the second most common cause of visual loss classified under retinal vascular disorders after diabetic retinopathy, and its complication, macular edema(ME), is the leading cause of vision loss. Currently, the first-line treatment for RVO-ME is the intravitreal injection of anti-vascular endothelial growth factor drugs, which can improve retinal morphology and patients' vision. Optical coherence tomography(OCT)can clearly image retinal structures, and some specific imaging features found by OCT have become biomarkers for evaluating the prognosis of RVO patients. The recent findings of biomarkers are reviewed, such as central retinal thickness, choroidal thickness, disorganization of retinal inner layers, hyperreflective foci, integrity of external limiting membrane and ellipsoid zone, central macular volume, prominent middle limiting membrane, paracentral acute middle maculopathy, highly reflective line, to provide references for selecting the best treatment for RVO.

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Mei Sun, Xiao-Feng Hao, Li-Ke Xie, et al. Research progress on optical coherence tomography imaging indicators of macular edema secondary to retinal vein occlusion. Guoji Yanke Zazhi( Int Eye Sci) 2023;23(1):58-61

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Publication History
  • Received:April 17,2022
  • Revised:December 05,2022
  • Adopted:
  • Online: January 04,2023
  • Published: