Statistical predictive model nomogram applied in ophthalmology
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    Abstract:

    The alignment diagram, also known as nomogram, is a statistical prediction model used to predict the risk of events(such as diagnosis or prediction of disease development and consequences)by obtaining the influence power of each related factor on outcome variables through multivariate analysis. Nomogram turns the complex regression equation to a visualized diagram that is intuitive and easy to understand. It is convenient to be used for evaluating the patient's condition and communicating with doctors and patients. With rapid advances of medical science and technology and increasing demands of personalized medicine, nomograms has attracted more and more attention and applied extensively in clinical medicine. This short article introduces the basic concepts of nomogram and examples of its application in ophthalmology.

    Reference
    1 Harrison K, Stein HA. A nomogram for fitting fluorosilicone acrylate contact lenses. CLAO J 1988; 14(3):136-138<br>2 Zhao Y, Yu R, Sun C, et al. Nomogram model predicts the risk of visual impairment in diabetic retinopathy: a retrospective study. BMC Ophthalmol 2022; 22(1):478 <br>3 Gabrielle PH, Massin P, Arnould L, et al. Development of a 1-year risk-prediction nomogram for good functional response with anti-VEGF agents in naive diabetic macular oedema. Acta Ophthalmol 2020; 98(8):e975-e982<br>4 Li Z, Deng X, Zhou L, et al. Nomogram-based prediction of clinically significant macular edema in diabetes mellitus patients. Acta Diabetol 2022; 59(9):1179-1188 <br>5 Li Y, Guo C, Huang C, et al. Development and evaluation of the prognostic nomogram to predict refractive error in patients with primary angle-closure glaucoma who underwent cataract surgery combined with goniosynechialysis. Front Med(Lausanne) 2021; 8:749903 <br>6杨惠春,宋学英,齐绍文,等.晶状体溶解性青光眼患者白内障手术后高眼压的危险因素. 国际眼科杂志 2021; 21(12):2170-2174<br>7鲜依鲆,周杨琳,姚曼. 2型糖尿病患者白内障术后干眼的风险模型构建.国际眼科杂志 2022; 22(4):23-26<br>8 Fernández J, Peris-Martínez C, Pérez-Rueda A, et al. Evaluation of a new nomogram for Ferrara ring segment implantation in keratoconus. Int J Ophthalmol 2021; 14(9):1371-1383<br>9 Guo C, Ye Y, Yuan Y, et al. Development and validation of a novel nomogram for predicting the occurrence of myopia in schoolchildren: A prospective cohort study. Am J Ophthalmol 2022; 242:96-106<br>10 Liu L, Li R, Huang D, et al. Prediction of premyopia and myopia in Chinese preschool children: a longitudinal cohort. BMC Ophthalmol 2021; 21(1):283<br>11 Huang Y, Li X, Fang W, et al. Development and validation of a simple nomogram for predicting rapid myopia progression in children with orthokeratology management. Curr Eye Res 2023; 48(5):465-473<br>12 Gao ZQ, Wu PY, Zhang J, et al. Nomogram for predicting nonproliferative vitreoretinopathy probability after vitrectomy in eyes with rhegmatogenous retinal detachment. Int J Ophthalmol 2023; 16(2):215-223<br>13 Zeng Q, Yao Y, Zhao M. Development and validation of a nomogram to predict cancer-specific survival of uveal melanoma. BMC Ophthalmol 2021; 21(1):230<br>14 Kong D, Li L, Wang H, et al. Immunological significance of survival-related alternative splicing in uveal melanoma. Aging(Albany NY) 2022; 14(2):811-825<br>15 Cui YY, Wang B, Jiang B, et al Nomogram model for predicting oculomotor nerve palsy in patients with intracranial aneurysm. Int J Ophthalmol 2022; 15(8):1316-1321
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Yan-Nian Hui. Statistical predictive model nomogram applied in ophthalmology. Guoji Yanke Zazhi( Int Eye Sci) 2023;23(7):1061-1063

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Publication History
  • Received:April 19,2023
  • Revised:May 25,2023
  • Online: June 21,2023