Home > Archive>Volume 24, Issue 12, 2024 >1954-1958. DOI:10.3980/j.issn.1672-5123.2024.12.17
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Changes of corneal densitometry in patients with keratoconus after corneal collagen cross-linking
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Fundamental Research Funds for the Central Universities, North Minzu University(No.2023XYZYX04); Ningxia Natural Science Foundation(No.2023AAC03450); Key Research and Development Program of Ningxia(No.2022BSB03042)

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    Abstract:

    AIM: To observe the changes of corneal densitometry(CD)in patients with keratoconus after corneal cross-linking(CXL).

    METHODS: Retrospective study. A total of 32 patients(43 eyes)with keratoconus in Ningxia Eye Hospital from April 2020 to April 2022 were selected. Pentacam analysis system divided the cornea into three layers: anterior 120 μm, middle layer and posterior 60 μm, and divides it into five regions with diameters of 0-2, 2-6, 6-10, 10-12 mm and full diameter according to the diameter, and measures the CD in different ranges. The changes of CD were compared before operation and at 1, 3 and 6 mo after operation.

    RESULTS: There were differences in uncorrected visual acuity, best corrected visual acuity and intraocular pressure before and 6 mo after operation(all P<0.05), and there was no difference in corneal endothelial cells(P=0.477). CD reached its peak at 1 mo after operation, and decreased at 3 mo and 6 mo after operation, but it was still higher than that before operation. There is a significant positive correlation between CD and Kmax in the anterior layer and the whole layer(r=0.164, P=0.016; r=0.152, P=0.023).

    CONCLUSION: The values of CD peaked at 1 mo after CXL, then it gradually decreased, tending to become stable at 6 mo postoperatively.

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Li Shuai, Gao Yang, Ma Limei,/et al.Changes of corneal densitometry in patients with keratoconus after corneal collagen cross-linking. Guoji Yanke Zazhi( Int Eye Sci) 2024;24(12):1954-1958

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Publication History
  • Received:June 09,2024
  • Revised:October 25,2024
  • Online: November 13,2024
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