Effect of heat shocｋ protein-７０on lens epithelial cells in huｍan diabetic cataract
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Effectof heat shock Protein-70on lens ePithelial cells in human diabetic cataract. Int JoPhthalmol
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Abstract:
to studythe effectof heat shock Protein-70(HSP-70)on lens ePithelial cells (LECs) in human diabetic cataract . ·METHODS:the exPressionof HSP-70 was assayed by using immunohistochemistry (strePtavidin-alkaline PhosPh- atase, S-P) in human diabetic cataract LECs (23 cases) and human normal LECs (7 cases). ·RESULTS:the exPressionof HSP-70 (x 2= 24.67, P < 0.01) was significant in diabetic human LECs (23 cases) butthere was no exPressionof HSP-70 in normal human LECs (7 cases). ·CONCLUSION: HSP-70 may Play a critical role inthe develoPment and formationof human diabetic cataract.
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Guo-Xing Xu, Jian-Zhang Hu, ting-Ting Wang, et al. Effect of heat shocｋ protein-７０on lens epithelial cells in huｍan diabetic cataract. Int J Ophthalmol, 2008,1(3):234-236
