Effect of head tilt on repeatability of optic nerve head parameters using cirrus spectral-domain optical coherence tomography
Author:
Corresponding Author:

Lilian Hui Li Koh. Department of Ophthalmology, Tan Tock Seng Hospital, National Healthcare Group Eye Institute, 11 Jalan Tan Tock Seng, 308433, Singapore. lilian.koh@mohh.com.sg

  • Article
  • | |
  • Metrics
  • |
  • Reference [24]
  • |
  • Related [20]
  • | | |
  • Comments
    Abstract:

    AIM: To assess the repeatability of measuring optic nerve head (ONH) parameters using the Cirrus optical coherence tomography (OCT), as well as to assess the effect of head tilt on these measurements. METHODS: Thirty healthy participants with no evidence of glaucoma were recruited for the study. Visual acuity, intraocular pressure, standard automated perimetry and ocular examination were performed for each participant. One eye was then randomly selected and scanned undilated with the Cirrus OCT in 3 positions (neutral, 30° right tilt and 30° left tilt). RESULTS: Data collected from 29 eyes were used for analysis. One patient was omitted due to poor scan quality. The repeatability of the ONH parameters was analyzed using analysis of variance, coefficient of variation (COV) and intraclass correlation coefficient (ICC). Analysis of variance showed no statistically significant difference between 3 scans in a single position. There was good agreement between measurements (ICC 0.919-0.996, COV 1.94%-5.48%). Even with the presence of head tilt, repeated scans in the 3 positions showed good agreement as well (ICC 0.888-0.996, COV 2.04%-5.39%). CONCLUSION: Serial measurements of ONH parameters using the Cirrus OCT are found to have good repeatability. The ONH parameters with Cirrus OCT also maintain good repeatability despite head tilt.

    Reference
    1 European Glaucoma Society. Terminology and Guidelines for Glaucoma. 3rd ed. Savona, Italy: Editrice Dogma; 2008.
    2 Medeiros FA, Zangwill LM, Bowd C, Vessani RM, Susanna R Jr, Weinreb RN. Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography. Am J Ophthalmol 2005;139(1):44-55.
    3 Tan BB, Natividad M, Chua KC, Yip LW. Comparison of retinal nerve fiber layer measurement between 2 spectral domain OCT instruments. J Glaucoma 2012;21(4):266-273.
    4 Hwang YH, Lee JY, Kim YY. The effect of head tilt on the measurements of retinal nerve fibre layer and macular thickness by spectral-domain optical coherence tomography. Br J Ophthalmol 2011;95(11):1547-1551.
    5 Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol Bull 1979;86(2):420-428.
    6 Bland JM, Altman DG. Measurement error. BMJ 1996;313(7059):744.
    7 Keltner JL, Johnson CA, Anderson DR, Levine RA, Fan J, Cello KE, Quigley HA, Budenz DL, Parrish RK, Kass MA, Gordon MO; Ocular Hypertension Treatment Study Group. The association between glaucomatous visual fields and optic nerve head features in the Ocular Hypertension Treatment Study. Ophthalmology 2006;113(9):1603-1612.
    8 Leske MC, Heijl A, Hussein M, Bengtsson B, Hyman L, Komaroff E; Early Manifest Glaucoma Trial Group. Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol 2003;121(1):48-56.
    9 Bizios D, Heijl A, Bengtsson B. Integration and fusion of standard automated perimetry and optical coherence tomography data for improved automated glaucoma diagnostics. BMC Ophthalmol 2011;11:20.
    10 Jonas JB, Bergua A, Schmitz-Valckenberg P, Papastathopoulos KI, Budde WM. Ranking of optic disc variables for detection of glaucomatous optic nerve damage. Invest Ophthalmol Vis Sci 2000;41(7):1764-1773.
    11 Park SB, Sung KR, Kang SY, Kim KR, Kook MS. Comparison of glaucoma diagnostic Capabilities of Cirrus HD and Stratus optical coherence tomography. Arch Ophthalmol 2009;127(12):1603-1609.
    12 Vizzeri G, Weinreb RN, Gonzalez-Garcia AO, Bowd C, Medeiros FA, Sample PA, Zangwill LM. Agreement between spectral-domain and time-domain OCT for measuring RNFL thickness. Br J Ophthalmol 2009;93(6):775-781.
    13 Hong S, Kim CY, Lee WS, Seong GJ. Reproducibility of peripapillary retinal nerve fiber layer thickness with spectral domain cirrus high-definition optical coherence tomography in normal eyes. Jpn J Ophthalmol 2010;54(1):43-47.
    14 Carpineto P, Nubile M, Agnifili L, Toto L, Aharrh-Gnama A, Mastropasqua R, Di Antonio L, Fasanella V, Mastropasqua A. Reproducibility and repeatability of Cirrus? HD-OCT peripapillary retinal nerve fibre layer thickness measurements in young normal subjects. Ophthalmologica 2012;227(3):139-145.
    15 Olmedo M, Cadarso-Suarez C, Gomez-Ulla F, Val C, Fernandez I. Reproducibility of optic nerve head measurements obtained by optical coherence tomography. Eur J Ophthalmol 2005;15(4):486-492.
    16 Paunescu LA, Schuman JS, Price LL, Stark PC, Beaton S, Ishikawa H, Wollstein G, Fujimoto JG. Reproducibility of nerve fiber thickness, macular thickness, and optic nerve head measurements using Stratus OCT. Invest Ophthalmol Vis Sci 2004;45:1716-1724.
    17 Lin D, Leung CK, Weinreb RN, Cheung CY, Li H, Lam DS. Longitudinal evaluation of optic disc measurement variability with optical coherence tomography and confocal scanning laser ophthalmoscopy. J Glaucoma 2009;18(2):101-106.
    18 Savini G, Carbonelli M, Parisi V, Barboni P. Repeatability of optic nerve head parameters measured by spectral-domain OCT in healthy eyes. Ophthalmic Surg Lasers Imaging 2011;42(3):209-215.
    19 Mwanza JC, Chang RT, Budenz DL, Durbin MK, Gendy MG, Shi W, Feuer WJ. Reproducibility of peripapillary retinal nerve fiber layer thickness and optic nerve head parameters measured with cirrus HD-OCT in glaucomatous eyes. Invest Ophthalmol Vis Sci 2010;51(11):5724-5730.
    20 Gonzalez-Garcia AO, Vizzeri G, Bowd C, Medeiros FA, Zangwill LM, Weinreb RN. Reproducibility of RTVue retinal nerve fiber layer thickness and optic disc measurements and agreement with Stratus optical coherence tomography measurements. Am J Ophthalmol 2009;147(6):1067-1074.
    21 Crowston JG, Hopley CR, Healey PR, Lee A, Mitchell P; Blue Mountains Eye Study. The effect of optic disc diameter on vertical cup to disc ratio percentiles in a population based cohort: the Blue Mountains Eye Study. Br J Ophthalmol 2004;88(6):766-770.
    22 Hoffmann EM, Zangwill LM, Crowston JG, Weinreb RN. Optic disk size and glaucoma. Surv Ophthalmol 2007;52(1):32-49.
    23 Henderer JD, Liu C, Kesen M, Altangerel U, Bayer A, Steinmann WC, Spaeth GL. Reliability of the disk damage likelihood scale. Am J Ophthalmol 2003;135(1):44-48.
    24 Hwang YH, Song M, Kim DW, Uhm KB. Retinal nerve fiber layer thickness measurement repeatability for Cirrus HD-OCT retinal tracking system during eye movement. J Glaucoma 2016;25(3):e214-219.
    Cited by
    Comments
    Comments
    分享到微博
    Submit
Get Citation

Lilian Hui Li Koh, Muhammad Amir Ismail, Sae Cheong Yap,/et al.Effect of head tilt on repeatability of optic nerve head parameters using cirrus spectral-domain optical coherence tomography. Int J Ophthalmol, 2016,9(8):1170-1175

Copy
Share
Article Metrics
  • Abstract:1627
  • PDF: 669
  • HTML: 0
  • Cited by: 0
Publication History
  • Received:July 19,2015
  • Revised:September 14,2015
  • Online: August 15,2016