Ruthenium-106 plaque brachytherapy for the treatment of diffuse choroidal hemangioma in Sturge-Weber syndrome

doi:10.18240/ijo.2020.03.22

Home > Archive>Volume 13, Issue 3, 2020 >513-517. DOI:10.18240/ijo.2020.03.22

Ruthenium-106 plaque brachytherapy for the treatment of diffuse choroidal hemangioma in Sturge-Weber syndrome
DOI:
                        10.18240/ijo.2020.03.22
                    
Author:
                        Ying-Ying YuYing-Ying Yu
Department of Ophthalmology & Clinical Center of Optometry, Peking University People’s Hospital, Beijing 100044, China; Eye Diseases and Optometry Institute Peking University People’s Hospital, Beijing 100044, China; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China; College of Optometry, Peking University Health Science Center, Beijing 100191, China
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Xiao-Xin LiXiao-Xin Li
Department of Ophthalmology & Clinical Center of Optometry, Peking University People’s Hospital, Beijing 100044, China; Eye Diseases and Optometry Institute Peking University People’s Hospital, Beijing 100044, China; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China; College of Optometry, Peking University Health Science Center, Beijing 100191, China
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Jian-Hong LiangJian-Hong Liang
Department of Ophthalmology & Clinical Center of Optometry, Peking University People’s Hospital, Beijing 100044, China; Eye Diseases and Optometry Institute Peking University People’s Hospital, Beijing 100044, China; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China; College of Optometry, Peking University Health Science Center, Beijing 100191, China
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Corresponding Author:Jian-Hong Liang. Department of Ophthalmology, Peking University People’s Hospital, No.11 Xizhimen South Avenue, Xicheng District, Beijing 100044, China. drliangjianhong@126.com
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Abstract:

AIM: To evaluate the efficacy of ruthenium-106 plaque brachytherapy for the treatment of diffuse choroidal hemangioma (DCH) in Sturge-Weber syndrome (SWS). METHODS: A total of 8 patients with DCH in SWS managed with plaque brachytherapy were retrospectively included. Patients were treated with ruthenium-106 plaque therapy (median apex dose: 83 Gy) at the thickest tumor region. On follow-up, we recorded the tumor thickness, the best-corrected visual acuity (BCVA), subretinal fluid (SRF) status, and complications following treatment. RESULTS: At a median follow-up of 43mo, tumor regression was observed in all cases, with a complete resolution of SRF and reduction in tumor-thickness. No radiation complications were recorded during the follow up time. CONCLUSION: Ruthenium-106 plaque therapy to the thickest portion of the tumor seems to be a useful treatment in patients with DCH in SWS.

Key words:diffuse choroidal hemangioma; Sturge-Weber syndrome; plaque brachytherapy

Reference

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Ying-Ying Yu, Xiao-Xin Li, Jian-Hong Liang. ,/et al.Ruthenium-106 plaque brachytherapy for the treatment of diffuse choroidal hemangioma in Sturge-Weber syndrome. Int J Ophthalmol, 2020,13(3):513-517

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Received:April 27,2019
Revised:November 17,2019
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Online: February 04,2020
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