Home > Archive>Volume 17, Issue 3, 2024 >408-419. DOI:10.18240/ijo.2024.03.02
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Artificial intelligence for the detection of glaucoma with SD-OCT images: a systematic review and Meta-analysis
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Ming-Fang Cao and Guang-Hui Liu. Department of Ophthalmology, Affiliated People’s Hospital (Fujian Provincial People’s Hospital), Fujian University of Traditional Chinese Medicine, 602 817 Middle Road, Taijiang District, Fuzhou 350004, Fujian Province, China. farrahcao@126.com; latiny@gmail.com

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    Abstract:

    AIM: To quantify the performance of artificial intelligence (AI) in detecting glaucoma with spectral-domain optical coherence tomography (SD-OCT) images. METHODS: Electronic databases including PubMed, Embase, Scopus, ScienceDirect, ProQuest and Cochrane Library were searched before May 31, 2023 which adopted AI for glaucoma detection with SD-OCT images. All pieces of the literature were screened and extracted by two investigators. Meta-analysis, Meta-regression, subgroup, and publication of bias were conducted by Stata16.0. The risk of bias assessment was performed in Revman5.4 using the QUADAS-2 tool. RESULTS: Twenty studies and 51 models were selected for systematic review and Meta-analysis. The pooled sensitivity and specificity were 0.91 (95%CI: 0.86–0.94, I2=94.67%), 0.90 (95%CI: 0.87–0.92, I2=89.24%). The pooled positive likelihood ratio (PLR) and negative likelihood ratio (NLR) were 8.79 (95%CI: 6.93–11.15, I2=89.31%) and 0.11 (95%CI: 0.07–0.16, I2=95.25%). The pooled diagnostic odds ratio (DOR) and area under curve (AUC) were 83.58 (95%CI: 47.15–148.15, I2=100%) and 0.95 (95%CI: 0.93–0.97). There was no threshold effect (Spearman correlation coefficient=0.22, P>0.05). CONCLUSION: There is a high accuracy for the detection of glaucoma with AI with SD-OCT images. The application of AI-based algorithms allows together with “doctor+artificial intelligence” to improve the diagnosis of glaucoma.

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Nan-Nan Shi, Jing Li, Guang-Hui Liu,/et al.Artificial intelligence for the detection of glaucoma with SD-OCT images: a systematic review and Meta-analysis. Int J Ophthalmol, 2024,17(3):408-419

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Publication History
  • Received:August 16,2023
  • Revised:December 18,2023
  • Online: February 27,2024
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