Treatment of uveitis and scleritis patients in Malaysia
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Iqbal Tajunisah. Department of Ophthalmology, University Malaya Eye Research Centre (UMERC), Faculty of Medicine, Universiti Malaya, Lembah Pantai, Kuala Lumpur 59100, Federal Territory of Kuala Lumpur, Malaysia. tajun69@yahoo.com

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    Abstract:

    AIM: To determine the common causes and visual outcome after treatment among uveitis and scleritis patients. METHODS: This is a retrospective cohort observational study. All consecutive clinical records of patients with newly diagnosed uveitis and scleritis over a 4-year period, from Jan. 1, 2017 to Dec. 31, 2020, were analysed. Data was collected at the presentation and included a follow-up period of one year. RESULTS: A total of 288 patients were recruited during the study period. Anterior uveitis was the most common anatomical diagnosis (50.0%) followed by panuveitis (25.0%), scleritis (13.5%), posterior uveitis (6.9%), and intermediate uveitis (4.5%). Viral Herpes was the most common cause of infectious cases, while Vogt-Koyanagi-Harada (VKH) disease and human leucocyte antigen (HLA) B27 spondyloarthropathy were the leading causes of identifiable non-infectious cases. Majority of patients presented with unilateral, non-granulomatous uveitis with an absence of hypopyon. Anatomical locations like posterior uveitis and panuveitis, and visual acuity worse than 3/60 at presentation were the factors associated with poor visual outcomes (P<0.05). About 60% of patients had an identifiable cause for the uveitis and scleritis, with nearly equal distribution of infectious (n=85, 29.5%) and non-infectious causes (n=84, 29.2%). About 14.5% of patients were clinically blind at 1y of follow-up. The most common complication in our uveitis patients was glaucoma (47.5%), followed by cystoid macula oedema (18.9%) and cataract (13.9%). CONCLUSION: Uveitis and scleritis are important causes of ocular morbidity. They are potentially blinding diseases which can have a good outcome if diagnosed and treated early.

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Sieng Teng Seow, Iqbal Tajunisah, Fei Yee Lee, et al. Treatment of uveitis and scleritis patients in Malaysia. Int J Ophthalmol, 2024,17(3):518-527

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Publication History
  • Received:September 23,2023
  • Revised:December 05,2023
  • Adopted:
  • Online: February 27,2024
  • Published: