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Volume 18,Issue 8,2025 Table of Contents

   
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Basic Research

Impact of microgravity on retinal neuroimmune responses and visual dysfunction in rats
  Jin-Shuo Liu, Nai-Qin Yan, Ying-Yan Mao, Chen Xin, Da-Peng Mou, Xin-Xiao Gao, Jia Guo, Ning-Li Wang, Si-Quan Zhu
  2025,18(8):1409-1425 [Abstract]  [View PDF(5.69 M)]  [PMC FullText]  [HTML]
  
Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways
  Dan Zhu, Xiao-Yang Wu, Liang-Chang Li
  2025,18(8):1426-1432 [Abstract]  [View PDF(2.03 M)]  [PMC FullText]  [HTML]
  
Damaging effect of ischemia on the development of retinal organoids derived from human embryonic stem cells
  Yu-Han Yan, Hong-Yu Li, Li-Xiong Gao, Wen Li, Ling-Ping Zhao, Quan Zeng, Yu Luo, Tian-Tian Cui, Ru-Ge Zang, Zi Ye, Jia-Fei Xi, Wen Yue, Zhao-Hui Li
  2025,18(8):1433-1449 [Abstract]  [View PDF(15.62 M)]  [PMC FullText]  [HTML]
  

Clinical Research

Surgical outcome of a transposed lateral pendular flap for the reconstruction of medial and central lower lid defects
  Yomna Amr Alahmadawy, Radwa Taher Elzanaty, Shaimaa Abdelsalam Arfeen
  2025,18(8):1450-1455 [Abstract]  [View PDF(1.45 M)]  [PMC FullText]  [HTML]
  
Association of interferon regulatory factor 8 dysregulation with dry eye in Sjögren’s syndrome
  Jiao Wang, Guang-Hong Chu, Zi-Huan Wang, Xiao-Yu Cai, Si-Yuan Shi, Qi-Ping Qing, Qi Zhang
  2025,18(8):1456-1463 [Abstract]  [View PDF(1.26 M)]  [PMC FullText]  [HTML]
  
Quantifying latanoprost-induced conjunctival hyperemia by anterior segment optical coherence tomography angiography
  Zakieh Vahedian, Ali Azimi, Seyed Mehdi Tabatabaei, Ghasem Fakhraie
  2025,18(8):1464-1469 [Abstract]  [View PDF(966.07 K)]  [PMC FullText]  [HTML]
  
Identification of novel drug targets for primary open angle glaucoma and its potential side-effects by human plasma proteome
  Da-Dong Jia, Qing-Ao Xiao, Shi-Yi Song, Meng Pan, Hao Hu, Kai-Li Wu, Jia-Bing Ran, Liang Liang
  2025,18(8):1470-1477 [Abstract]  [View PDF(1.67 M)]  [PMC FullText]  [HTML]
  
Preliminary assessment of the safety and effectiveness of artificial iris implantation
  Si-Yi Wang, Mi-Mi Liu, Xi-Le Li, Chao-Xiang Ge, Wei Chen, Zhen-Quan Zhao
  2025,18(8):1478-1483 [Abstract]  [View PDF(904.23 K)]  [PMC FullText]  [HTML]
  
Does uveitis increase the risk of age-related wet macular degeneration? A Mendelian randomization study
  Rui-Hua Jing, Deng-Ke Zhou, Zhuo-Yan Yang, Zhao-Dan Ding, Jia-Hui Deng, Yao Xing, Xiao-Feng Chen
  2025,18(8):1484-1489 [Abstract]  [View PDF(881.09 K)]  [PMC FullText]  [HTML]
  
Quantitative characterization of types 1 and 2 macular neovascularization in neovascular age-related macular degeneration with intravitreal conbercept: an analysis utilizing optical coherence tomography angiography
  Yan-Mei Shi, Xiao Xie, Wen-Qi Wang, Xiao-Meng Yuan, Zhi-Ping Zhang, Hong-Yan Wang, Jie Meng, Ze-Hao Kong, Xia Jing, Ting-Ting Liu
  2025,18(8):1490-1497 [Abstract]  [View PDF(1.73 M)]  [PMC FullText]  [HTML]
  
Systemic C-reactive protein levels in patients with geographic atrophy stratified by sex
  Ramya Gnanaraj, Alan G. Palestine, Brandie D. Wagner, Jennifer L. Patnaik, Talisa E. de Carlo Forest, Marc T. Mathias, Niranjan Manoharan, Vivian Rajeswaren, Naresh Mandava, Anne M. Lynch
  2025,18(8):1498-1505 [Abstract]  [View PDF(917.12 K)]  [PMC FullText]  [HTML]
  
Combination of red blood cell distribution width and platelet-to-lymphocyte ratio for predicting severity of diabetic retinopathy
  Zhi-Mei Wei, Yu Zhao, Ran-Ran Ding, Yu-Song Zeng, Zheng Zeng, Zi-Tong He, Jing Hao, Jing-Jing Hu, Jin-Guo Yu, Cai-Yun You
  2025,18(8):1506-1514 [Abstract]  [View PDF(1.33 M)]  [PMC FullText]  [HTML]
  
Long-term retinal microvascular alterations after endoscopic endonasal surgery in patients with sellar region tumors
  Sebnem Kaya Ergen, Anil Ergen, Busra Gunduz, Ecem Cemre Ceylan, Sevgi Subasi, Melih Caklili, Burak Cabuk, Ihsan Anik, Savas Ceylan
  2025,18(8):1515-1521 [Abstract]  [View PDF(644.00 K)]  [PMC FullText]  [HTML]
  
Ocular biological characteristics of children with myopia and rapid axial length changes treated with spectacles with highly aspherical lenslets
  Jing Zhai, Hao Chen, Xin-Jie Ye, Wei-Jun Cai, Li-Jie Hou, Mei-Xiao Shen, Fan Lyu
  2025,18(8):1522-1528 [Abstract]  [View PDF(874.03 K)]  [PMC FullText]  [HTML]
  
Choroidal response to optical defocus as a potential surrogate marker for myopia control effect
  Muteb K. Alanazi, Mohammed Alshehri, Mohammed Althomali, Mohammed Alhazmi, Mansour Alghamdi, Nawaf M. Almutairi, Basal Altoaimi, Ahmed Alharbi, Ali Almustanyir, Maria Liu
  2025,18(8):1529-1536 [Abstract]  [View PDF(1.42 M)]  [PMC FullText]  [HTML]
  
Comparison of asymmetric offset versus pupil centered ablation in refractive surgery
  Hassan Hashemi, Mojgan Pakbin, Alireza Hashemi, Mohammadreza Aghamirsalim, Mehdi Khabazkhoob
  2025,18(8):1537-1543 [Abstract]  [View PDF(921.91 K)]  [PMC FullText]  [HTML]
  
Nanopore targeted sequencing identifies pathogens in patients with postoperative endophthalmitis
  Xin-Lei Hao, Man Yuan, Ming Wang, Ai-Si Fu, Jia-Shuang Gu, Bing-Qian Yang, Wei Jin, An-Huai Yang
  2025,18(8):1544-1552 [Abstract]  [View PDF(574.73 K)]  [PMC FullText]  [HTML]
  
Endogenous endophthalmitis due to Klebsiella pneumoniae liver abscess: a retrospective study of clinical course, treatment pattern, and prognosis
  Gyu Chul Chung, Dong Sun Kim, Ji Eun Lee, Iksoo Byon, Sung Who Park, Han Jo Kwon, EunAh Kim
  2025,18(8):1553-1560 [Abstract]  [View PDF(1.36 M)]  [PMC FullText]  [HTML]
  

Investigation

Progression of myopia among school-aged children in Guangzhou, China
  Kun Huang, Zhi-Dan Wu, Ze-Hao Chen, Jin Chen, Zhuo-Ming Tang, Rong Lin
  2025,18(8):1561-1569 [Abstract]  [View PDF(600.12 K)]  [PMC FullText]  [HTML]
  

Review Article

Advances in treatment of adenoid cystic carcinoma of the lacrimal gland
  Jin-Bei Li, Jian-Min Ma
  2025,18(8):1570-1578 [Abstract]  [View PDF(1.44 M)]  [PMC FullText]  [HTML]
  
Mechanisms of fibrosis formation following glaucoma filtration surgery
  Wei-Dao Zhang, Xin Li, Jun Feng, Jie Chen
  2025,18(8):1579-1586 [Abstract]  [View PDF(1.02 M)]  [PMC FullText]  [HTML]
  
Etiology and management of uveitis-glaucoma-hyphema syndrome: a comprehensive review
  Jing-Ting Luo, Zhao-Xun Feng, Cong Wang
  2025,18(8):1587-1593 [Abstract]  [View PDF(433.69 K)]  [PMC FullText]  [HTML]
  
Deep learning applications for diabetic retinopathy and retinopathy of prematurity diseases diagnosis: a systematic review
  Elizabeth Ndunge Mutua, Bernard Shibwabo Kasamani, Christoph Reich
  2025,18(8):1594-1602 [Abstract]  [View PDF(1.53 M)]  [PMC FullText]  [HTML]
  

Letter to the Editor

Triple procedure for management of traumatic aphakia, glaucoma and mydriasis
  Bin Chen, Yan-Ting Li, Yun-Feng Lu
  2025,18(8):1603-1605 [Abstract]  [View PDF(1.34 M)]  [PMC FullText]  [HTML]
  
Nd:YAG laser peripheral iridotomy for reverse pupillary block: a case report
  Ze-Yu Zhang, Zhi-Qiao Liang, Yong-Zhen Bao
  2025,18(8):1606-1609 [Abstract]  [View PDF(973.85 K)]  [PMC FullText]  [HTML]
  
Two cases of lamellar macular hole secondary to the rupture of the cystoid inner wall in patients with diabetic macular edema
  Zhi-Hui Dong, Jia-Yu Zhang, Chao-Yang Zhang, Zhen-Guo Chen, Jing-Fa Zhang
  2025,18(8):1610-1612 [Abstract]  [View PDF(1.55 M)]  [PMC FullText]  [HTML]