Analysis of glistenings in hydrophobic acrylic intraocular lenses on visual performance
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State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China

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Supported bythe Science and Technology Plan of Guangdong Province, Guangzhou, China (No.2006B36006005)
Conflicts of Interest: Xi L, None; Liu Y, None; Zhao F, None; Chen C, None; Cheng B, None.
ACKNOWLEDGEMENTS: The authors thank Sherrina Patel for her helpful revision of the manuscript and thank the patients for their participant in the study.

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    Abstract:

    AIM:To assess patients’ visual performance with glistenings in one piece soft hydrophobic acrylic intraocular lenses (IOLs) (Alcon) 2 years postoperatively.METHODS:This cross section trial included 120 eyes with one piece IOL at 2 years postoperatively. Glistening was classified in 4 groups, ranging from 0 (none) to 3 (most evident) according to their severity in IOLs optics observed under a slit lamp. All eyes underwent a uncorrected and best-corrected visual acuity evaluation (UCVA and BCVA, LogMAR scale), a complete clinical examination, a contrast sensitivity (CS) evaluation by F.A.C.T chart, and a visual field test by Humphrey Field AnalyzerⅡ(HFA). One-way ANOVA was used for quantitative data, while Pearson χ2 test was used for qualitative data to analyze the visual function of 4 glistening groups.RESULTS: Totally 120 eyes were enrolled with 30 eyes in each glistening group. There was no statistical correlation between glistening grades and patients’ age, IOLs power, postoperative UCVA and BCVA (P>0.05). Quantificationally, CS values among each group were not statistically different. However, qualitative analysis showed there were more eyes in grade 3 group than in grade 0 group having abnormally declined CS at high spatial frequency (10% vs 36.7% at 18 cpd, P=0.029; 6.7% vs 26.7% at 12 cpd, P=0.013). Mean deviation (MD) of the visual field test was -2.14±2.31, -1.97±2.23, -3.02±3.17, -4.12±3.38 in group 0 to 3 respectively. There was a significant decrease in the most serious glistenings group (P =0.018).CONCLUSION:Glistenings may potentially have an impact on contrast sensitivity at high spatial frequencyand MD in visual field test.

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Lei Xi, Yi Liu, Feng Zhao, et al. Analysis of glistenings in hydrophobic acrylic intraocular lenses on visual performance. Int J Ophthalmol, 2014,7(3):445-451

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Publication History
  • Received:January 04,2014
  • Revised:April 05,2014
  • Adopted:April 05,2014
  • Online: June 24,2014
  • Published: