Ocular findings in syndromic gingival fibromatosis:a case study and electronic microscopic investigation of lens
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1Department of Neurology, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China;
2Eye Center, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China;
3Department of Stomatology, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China

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Supported by the Zhejiang Medical Science Research Foundation of China (No. 2009A108).
Conflicts of Interest: Tang YL, None; Shentu XC, None; Zhao SJ, None; Tang XJ, None; He L, None; Ping FY, None.

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    Abstract:

    We report a case of syndromic gingival fibromatosis with notable ocular lesions, bilateral congenital cataracts, esotropia, and high myopia of a 21-year-old male patient from China. The patient was diagnosed with gingival fibromatosis based on his massive gingival overgrowth and histological findings that were consistent with gingival fibromatosis through a gingival biopsy. Lens opacity features were presented and phacoemulsificaion with intraocular lens(IOL) implantation was performed to manage the cataracts in both eyes. Transmission electronic microscopy was used to investigate the ultrastructure of the removed lens tissue. We also review the literature on gingival fibromatosis and briefly summarize the ocular manifestations of this rare disease.

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Ye-Lei Tang, Xing-Chao Shentu, Su-Juan Zhao, et al. Ocular findings in syndromic gingival fibromatosis:a case study and electronic microscopic investigation of lens. Int J Ophthalmol, 2014,7(3):574-576

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Publication History
  • Received:March 25,2014
  • Revised:May 20,2014
  • Adopted:May 20,2014
  • Online: June 24,2014
  • Published: