25-gauge transconjunctival diagnostic vitrectomy in suspected cases of intraocular lymphoma:a case series and review of the literature
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1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1666663111, Iran;
2Central Eye Bank of Iran, Tehran 1968876711, Iran;
3 Cornea Service, Wills Eye Hospital, Philadelpheia 19107, USA

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Conflicts of Interest: Kanavi MR, None; Soheilian M, None; Hosseini SB, None; Azari AA, None.
ACKNOWLEDGEMENTS: The authors thank Mrs Kefayat Mohammadi Roshanagh for her assistance in this study.

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    Abstract:

    AIM: To report the cytology results of 25-gauge transconjunctival (25G-TSV) diagnostic vitrectomy in cases suspicious for intraocular lymphoma (IOL), and compare the results to those reported in the literature.METHODS: Clinical and cytopathological records of 18 vitreous biopsy specimens obtained via 25G-TSV diagnostic vitrectomy in 12 patients suspicious for IOL were reviewed retrospectively. A review of the literature in regards to the diagnostic yields of vitreous specimens obtained via 25-gauge and 20-gauge diagnostic vitrectomy in suspected cases of IOL was performed.RESULTS: Eighteen eyes from 12 patients with clinical suspicion of IOL underwent diagnostic 25G-TSV. The cytopathological investigations demonstrated IOL in 15 eyes (83.3%). Vitreous analysis was non-diagnostic in 3 eyes (16.7%).CONCLUSION: Twenty-five-gauge diagnostic vitrectomy yields adequate sample for cytological evaluation of the vitreous in cases suspicious for IOL. The diagnostic results of the 25G-TSV in the current study are superior to those reported for 20-gauge vitrectomy but equivalent to those reported for 25G-TSV in the published literature.

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Mozhgan Rezaei Kanavi, Masoud Soheilian, Sayed Bagher Hosseini, et al.25-gauge transconjunctival diagnostic vitrectomy in suspected cases of intraocular lymphoma:a case series and review of the literature. Int J Ophthalmol, 2014,7(3):577-581

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Publication History
  • Received:September 17,2013
  • Revised:April 22,2014
  • Adopted:April 22,2014
  • Online: June 24,2014
  • Published: