Vitreous substitutes:challenges and directions
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Supported by the “Twelfth Five-Year” Plan for Science & Technology Support Grant (No.2012BAI08B02); the National 863 Project (No.2009AA02Z404); the Guangdong Provincial Industry University Research Cooperation Plan (No.2010A090200074)

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    Abstract:

    Thenatural vitreous body has a fine structure and complex functions. The imitation of the natural vitreous body by vitreous substitutes is a challenging work for both researchers and ophthalmologists. Gases, silicone oil, heavy silicone oil and hydrogels, particularly the former two vitreous substitutes are clinically widely used with certain complications. Those, however, are not real artificial vitreous due to lack of structure and function like the natural vitreous body. This article reviews the situations, challenges, and future directions in the development of vitreous substitutes, particularly the experimental and clinical use of a new artificial foldable capsular vitreous body .

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Qian-Ying Gao, Yue Fu, Yan-Nian Hui. Vitreous substitutes:challenges and directions. Int J Ophthalmol, 2015,8(3):437-440

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Publication History
  • Received:January 19,2014
  • Revised:February 10,2014
  • Adopted:February 10,2014
  • Online: June 09,2015
  • Published: