Long-term follow-up of vitrectomy in patients with pathologic myopic foveoschisis
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Ge-Zhi Xu. Department of Ophthalmology and Visual Science, Eye, Ear, Nose, and Throat Hospital, 83 Fenyang Rd, Shanghai 200031, China. xugezhimf@163.com

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Supported by the National Key Basic Research Program of China (No.2013CB967503).

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    Abstract:

    AIM: To report the long-term surgical outcomes of pathologic myopic foveoschisis (MF) following vitrectomy. METHODS: We performed a retrospective case series analysis of 50 consecutive patients diagnosed with MF who experienced vision loss due to progression of foveoschisis. The 50 patients (67 eyes) were treated in our hospital with vitrectomy with internal limiting membrane (ILM) peeling from December 2004 to September 2010. Best corrected visual acuity (BCVA), refractive error, optical coherence tomography (OCT), and routine examination results were analysed. The changes of BCVA, foveal anatomical features on OCT scan, and complications were the main outcome measures. RESULTS: The mean follow-up duration was 42±17mo (range 24 to 93mo). BCVA improved significantly postoperatively (0.76±0.65 logMAR) compared with preoperative baselines (1.31±0.78 logMAR, P<0.0001), and in 53 eyes (79%) including 3 lines gain in 44 eyes (66%) at the last follow-up visit. OCT scans showed that central retinal thickness decreased from 580.0±270.0 μm preoperatively (n=67) to 179.7±84.7 μm postoperatively (n=58, P<0.0001). Total resolution of foveoschisis occurred in 41 eyes (61%). Preoperative BCVA correlated well with postoperative BCVA, whereas other factors such as age, axial length, and refractive error were not correlated. The most common complications were cataract and full-thickness macular hole formation in 14 and 9 cases, respectively. CONCLUSION: Patients with progressive vision loss due to MF who were treated with vitrectomy with ILM peeling show favourable outcomes. In most eyes, visual acuity and foveal structure remain stable during long-term observation.

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Ting Zhang, Ying Zhu, Chun-Hui Jiang, et al. Long-term follow-up of vitrectomy in patients with pathologic myopic foveoschisis. Int J Ophthalmol, 2017,10(2):277-284

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Publication History
  • Received:July 22,2016
  • Revised:November 08,2016
  • Adopted:
  • Online: February 10,2017
  • Published: