Amniotic membrane transplantation with topical interferon alfa-2b after excision of ocular surface squamous neoplasia
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Ming-Chang Zhang. Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1277 Jiefang Avenue, Wuhan 430022, China. mingchangzhang@hotmail.com

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Supported by National Natural Science Foundation of China (No.81300736; No.81370993).

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    Abstract:

    To evaluate the outcome of amniotic membrane transplantation (AMT) after tumor excision followed by topical interferon alfa-2b (IFNα2b) drops for primary ocular surface squamous neoplasia (OSSN). Twelve eyes of 12 patients with a mean age of 66±10y were included. The average follow-up was 23±10mo. All 12 patients had limbal involvement. Smooth ocular surface and transparent cornea were achieved in all cases. No sign of inflammation, neovascularization, symblepharon or recurrence was noted at the last follow-up. We conclude that AMT with topical IFNα2b drops restores a healthy ocular surface in OSSN without recurrence.

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Hua-Tao Xie, Ying-Ying Zhang, Dong-Ling Jiang, et al. Amniotic membrane transplantation with topical interferon alfa-2b after excision of ocular surface squamous neoplasia. Int J Ophthalmol, 2018,11(1):160-162

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Publication History
  • Received:March 14,2017
  • Revised:August 30,2017
  • Adopted:
  • Online: January 09,2018
  • Published: