Clinical outcome of combined conjunctival autograft transplantation and amniotic membrane transplantation in pterygium surgery
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Kai Hu. Department of Ophthalmology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing University, Nanjing 210008, Jiangsu Province, China; Nanjing Ningyi Eye Center, Nanjing 210008, Jiangsu Province, China. hukai70@163.com

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Supported by Natural Science Foundation of Jiangsu Province (No.BK20141346); Nanjing Science and Technology Development Plan (No.201402001).

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    Abstract:

    AIM: To compare long-term outcome of primary and recurrent pterygium surgery with three different techniques: combined conjunctival autograft and overlay amniotic membrane transplantation (CAT with AMT), conjunctival autograft transplantation (CAT) alone and amniotic membrane transplantation (AMT) alone. METHODS: In this retrospective study, 142 eyes of 142 pterygium patients (104 primary, 38 recurrent) who underwent CAT (group A), AMT (group B) or CAT with AMT (group C) respectively following surgical excision were reviewed and compared based on the recurrences and post-operative complications. RESULTS: The number of recurrence post-surgery were 17 (9 from primary, 8 from recurrent; the same description below), 18 (10, 8) and 2 (1, 1) in groups A, B, and C respectively; dry eyes were 22 (16, 6), 27 (18, 9) and 7 (3, 4); conjunctival inflammations were 30 (17, 13), 27 (16, 11) and 11 (6, 5). Patients in group C (either primary or recurrent or both) mainly showed significantly better results than those in group A or B (P<0.05) regarding above-mentioned clinical effects. CONCLUSION: Combined CAT and overly AMT have significantly lower rates of recurrence and postoperative complications for primary and recurrent pterygium surgery than CAT or AMT alone.

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Tejsu Malla, Jing Jiang, Kai Hu. Clinical outcome of combined conjunctival autograft transplantation and amniotic membrane transplantation in pterygium surgery. Int J Ophthalmol, 2018,11(3):395-400

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Publication History
  • Received:October 17,2017
  • Revised:January 12,2018
  • Adopted:
  • Online: March 13,2018
  • Published: