Autophagy: a potential target for the treatment of intraocular neovascularization
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Jun-Hui Du. Department of Ophthalmology, Xi’an Ninth Hospital Affiliated to Medical College of Xi’an Jiaotong University, Xi’an 710054, Shaanxi Province, China. djh79918@163.com

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Supported by the Natural Science Foundation of Shaanxi province (No.2016JM8018); the Natural Science Foundation of Xi’an Science Technology Bureau [(No.SF1508(3)].

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    Abstract:

    The formation of neovascularization is a common pathological feature of many ocular vascular diseases, and is an important cause of vision loss in patients. Neovascularization can cause retinal hemorrhage, vitreous hemorrhage, and other serious complications, leading to loss of vision. The treatment of intraocular neovascularization is the focus of ophthalmology research. In recent years, some studies have found that autophagy is closely related to vascular endothelial growth factor and the formation of neovascularization. Autophagy is expected to become a new target for the treatment of intraocular neovascularization. Therefore, this article reviews the research on autophagy and the formation of intraocular neovascularization.

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Xia-Ru Zhu, Jun-Hui Du. Autophagy: a potential target for the treatment of intraocular neovascularization. Int J Ophthalmol, 2018,11(4):695-698

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Publication History
  • Received:January 03,2018
  • Revised:January 29,2018
  • Adopted:
  • Online: April 10,2018
  • Published: