Ocular hypertension in patients with central/hemicentral retinal vein occlusions: cumulative prevalence and management
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Mihai C?lug?ru. Department of Ophthalmology, University of Medicine, Strada Brancoveanu 11, Cluj-Napoca 400467, Romania. mihai.calugaru@mail.dntcj.ro

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    Abstract:

    AIM: To prospectively evaluate the cumulative prevalence and the management of ocular hypertension (OH) in patients with unilateral acute central/hemicentral retinal vein occlusions (C/HCRVOs) over the course of 3y. METHODS: The study included 57 patients with unilateral acute C/HCRVOs. All patients underwent a comprehensive ophthalmological examination of both eyes. OH associated with C/HCRVO in patients showing a score >5% for the risk of conversion to primary open angle glaucoma (POAG) was treated with OH medication. The treatment aimed for a decrease in intraocular pressure (IOP) to <21 mm Hg with a >22% reduction from the initial values. The cumulative prevalence of OH and the effectiveness of treatment assessed by the cumulative prevalence of conversion from OH to POAG, were estimated. RESULTS: Fifteen patients had OH associated with C/HCRVOs, the cumulative prevalence of OH was 29.4% (95% confidence interval, 16.9-41.9). The mean value of the risk score of OH conversion to POAG for the 5 subsequent years was 11.7%±5.4%. The IOP significantly decreased from 25.67±2.16 mm Hg to 18.73±2.96 mm Hg. None of the OH patients converted to POAG during the follow-up period. CONCLUSION: The increased cumulative prevalence of OH in C/HCRVO patients indicates that OH is a risk factor for the appearance of venous occlusion. Patients with OH associated with C/HCRVO must be considered to be at high risk for conversion to POAG. Treatment with OH medications prevented conversion to POAG during the 3-year follow-up.

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Dan C&#;lug&#;ru, Mihai C&#;lug&#;ru,&#;tefan &#;&#;lu. Ocular hypertension in patients with central/hemicentral retinal vein occlusions: cumulative prevalence and management. Int J Ophthalmol, 2018,11(7):1173-1178

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Publication History
  • Received:January 11,2017
  • Revised:November 26,2017
  • Adopted:
  • Online: July 10,2018
  • Published: