Free autologous internal limiting membrane transplantation in the treatment of large macular hole
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Yu-Hua Hao. Department of Ophthalmology, Second Hospital of Hebei Medical University, 215 West Heping Road, Shijiazhuang 050000, Hebei Province, China. yuhuasjz@sina.com

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Supported by Hebei Science and Technology Department (Project to Benefit the People No.16277717D); Natural Science Foundation of Hebei Province (No.H2015206249); Second Hospital of Hebei Medical University (No.2h1201508).

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    Abstract:

    We evaluated the clinical efficacy of free internal limiting membrane (ILM) flap transplantation for the treatment of large macular hole over 500 μm in 42 consecutive patients. Quantified evaluation of the post-operative macular anatomy restoration was performed by spectral-domain optical coherence tomography in the 12mo follow-up. The results showed 41 eyes achieved successful closure (97.6%). Postoperative best corrected visual acuity, ellipsoid layer, and external limiting membrane disruption were significantly improved at all follow-up time points. The central foveal thickness was significantly higher at 1mo. We concluded that free ILM flap transplantation proves to be effective to achieve anatomical and functional improvement for the treatment of large macular hole.

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Fei-Yan Ma, Rui-Jie Xi, Peng-Fei Chen, et al. Free autologous internal limiting membrane transplantation in the treatment of large macular hole. Int J Ophthalmol, 2019,12(5):848-851

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Publication History
  • Received:July 10,2018
  • Revised:March 19,2019
  • Adopted:
  • Online: March 27,2019
  • Published: