Effect of lens constants optimization on the accuracy of intraocular lens power calculation formulas for highly myopic eyes
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Li-Xia Luo. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China. luolixia@mail.sysu.edu.cn

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Supported by National Natural Science Foundation of China (No.81770905). The funding organization had no role in the design or conduct of this research.

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    Abstract:

    AIM: To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens (IOL) power calculation formulas for highly myopic eyes. METHODS: This study comprised 108 eyes of 94 consecutive patients with axial length (AL) over 26 mm undergoing phacoemulsification and implantation of a Rayner (Hove, UK) 920H IOL. Formulas were evaluated using the following lens constants: manufacturer’s lens constant, User Group for Laser Interference Biometry (ULIB) constant, and optimized constant for long eyes. Results were compared with Barrett Universal II formula, original Wang-Koch AL adjustment method, and modified Wang-Koch AL adjustment method. The outcomes assessed were mean absolute error (MAE) and percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 diopter (D). The nonparametric method, Friedman test, was used to compare MAE performance among constants. RESULTS: Optimized constants could significantly reduce the MAE of SRK/T, Hoffer Q, and Holladay 1 formulas compared with manufacturer’s lens constant, whereas the percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 D had no statistically significant differences. Optimized lens constant for long eyes alone showed non-significant refractive advantages over the ULIB constant. Barrett Universal II formula and formulas with AL adjustment showed significantly higher accuracy in highly myopic eyes (P<0.001). CONCLUSION: Lens constant optimization for the subset of long eyes reduces the refractive error only to a limited extent for highly myopic eyes.

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Jia-Qing Zhang, Xu-Yuan Zou, Dan-Ying Zheng, et al. Effect of lens constants optimization on the accuracy of intraocular lens power calculation formulas for highly myopic eyes. Int J Ophthalmol, 2019,12(6):943-948

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Publication History
  • Received:July 21,2018
  • Revised:November 30,2018
  • Adopted:
  • Online: May 06,2019
  • Published: