Citation:Park SH,Che CY,Kim SI,Park CY,Lee JH,Kim YH,Jung JW,Lee JS,Lee JE.Comparison of clinical outcomes after femtosecond laser in situ keratomileusis in eyes with low or high myopia.Int J Ophthalmol 2020;13(11):1780-1787,doi:10.18240/ijo.2020.11.15
Comparison of clinical outcomes after femtosecond laser in situ keratomileusis in eyes with low or high myopia
Received:September 27, 2019  Revised:March 23, 2020
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DOI:10.18240/ijo.2020.11.15
Key Words:femtosecond laser  LASIK  myopia
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Su Hwan Park Department of Ophthalmology, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam Province, Republic of Korea; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Gyeongnam Province, Republic of Korea
Cheng-Ye Che Department of Ophthalmology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao , Shandong Province, China
Sung Il Kim Department of Ophthalmology, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam Province, Republic of Korea; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Gyeongnam Province, Republic of Korea
Choul Yong Park Department of Ophthalmology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang 10326, Gyeonggi Province, Republic of Korea
Jong Heon Lee Busan Medical Center, Busan 47527, Republic of Korea
Young Hee Kim BalGunNun Eye Hospital, Busan 47195, Republic of Korea
Ji Won Jung BalGunNun Eye Hospital, Busan 47195, Republic of Korea
Jong Soo Lee Department of Ophthalmology, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam Province, Republic of Korea
Ji Eun Lee Department of Ophthalmology, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam Province, Republic of Korea; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Gyeongnam Province, Republic of Korea
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Abstract:
      AIM: To compare the clinical results of femtosecond (FS) laser in situ keratomileusis (LASIK) in high myopic patients and low myopic patients.

    METHODS: This study included 212 myopic eyes undergoing LASIK using a VisuMax 500kHz FS laser. All treated eyes were assigned to one of two groups according to preoperative manifest spherical refraction: low myopia group (A, >?4.0 D) and high myopia group (B, ≤?4.0 D). Uncorrected and corrected distance visual acuity (UDVA, CDVA), refractive errors, and higher-order aberrations (HOAs) were measured preoperatively and 1wk, 1, 3 and 6mo postoperatively.

    RESULTS: At 6mo of follow-up, 92% and 76% had a UDVA of 20/20 or better in group A and B, respectively (P=0.037) and UDVA was significantly different between two groups (P=0.042). Six and seven percentage lost one line of CDVA in group A and B, respectively (P=0.572) and no eyes in both groups lost more than two lines. Each group had 87% and 76% of treated eyes within ±0.5 D of the intended correction (P=0.186), and 13% and 43% with a change of >0.50 D in spherical equivalent from 1wk to 6mo postoperatively (P=0.005). In terms of postoperative astigmatism, each group had 89.1% and 76.6% within ±0.50 D, respectively and there was significant difference (P=0.006). Group A tends to induce smaller HOAs than group B.

    CONCLUSION: FS LASIK is effective and safe for correcting high myopia as well as low myopia. However, high myopic eyes showed more postoperative astigmatism and HOAs which affect visual acuity.

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