Comparison of healing patterns of different side-cut angulations after FS-LASIK
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Di Shen. Xi’an No.1 Hospital, First Affiliated Hospital of Northwestern University, 30 Fenxiang, the South Street, Beilin District, Xi’an 710002, Shaanxi Province, China. shendi_sddy@126.com

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Supported by the Science and Technology Program of Xi’an, China [No.201805097YX5SF31(2)]; the Foundation of Shaanxi Province Key Research and Development Project (No.2018SF-216).

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    Abstract:

    AIM: To investigate and evaluate healing patterns around flaps made with different side-cut angulations after femtosecond laser in situ keratomileusis (FS-LASIK). METHODS: Thirty-four patients (68 eyes) received a 90° side-cut (n=34) or a 120° side-cut flaps (n=34) made with a femtosecond laser. One day, 1wk, 1 and 3mo postoperatively, side-cut scar was evaluated under slit-lamp photography according to a new grading system (Grade 0=transparent scar, 1=faint healing opacity, and 2=evident healing opacity). In vivo corneal confocal microscopy and anterior segment optical coherence tomography (AS-OCT) were used to observe wound-healing patterns around flap margin in the two groups. Sirius Scheimpflug Analyzer was also used to analyze higher order aberrations 3mo after surgery. RESULTS: There were no significant differences in flap wound-healing patterns at each follow up between the two groups (P>0.05). Three months after surgery, the flap edge scar classified as Grade 0 had excellent apposition and rapid nerve regeneration. At 3 mm and 5 mm pupil diameters, there were significant differences in trefoil aberrations between the two groups (P<0.05), but no statistically significant differences were found in total higher order aberrations (HOAs), spherical aberrations or coma in any of the pupil size conditions (P>0.05). CONCLUSION: Flap edge scars classified as Grade 0 have excellent apposition and rapid nerve regeneration, and 120° side-cut angle flaps induce less trefoil aberrations after FS-LASIK.

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Wei Wei, Xi-Yu Sun, Di Shen, et al. Comparison of healing patterns of different side-cut angulations after FS-LASIK. Int J Ophthalmol, 2021,14(3):430-435

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Publication History
  • Received:January 19,2020
  • Revised:June 05,2020
  • Adopted:
  • Online: February 24,2021
  • Published: