Anterior segment OCT application in quantifying posterior capsule opacification severity with varied intraocular lens designs
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Xiao-Yong Yuan. Tianjin Eye Hospital, No.4 Gansu Road, Heping District, Tianjin 300020, China. yuanxy_cn@hotmail.com

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Supported by the Science and Technology Foundation of Tianjin Eye Hospital (No.YKQN2003).

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    Abstract:

    AIM: To evaluate the application of anterior segment-optical coherence tomography (AS-OCT) in posterior capsule opacification (PCO) severity assessment and analyse the relationship between PCO severity and intraocular lens (IOL) characters. METHODS: PCO patients were prospectively recruited. Cross-sectional images of the anterior segment at horizontal and vertical meridians were acquired with AS-OCT. The area of the IOL-PC (posterior capsular) space and PCO severity (area, thickness, and density at 3 mm and 5 mm IOL optic regions) were measured. The relationship between PCO severity and visual acuity, comparisons of PCO severity and IOL-PC space using varied IOL designs were analysed. RESULTS: One hundred PCO eyes were enrolled. IOL-PC space, PCO thickness and area were positively correlated with axial length. In addition, PCO area and thickness were positively correlated with visual acuity when it was ≤0.52 logMAR. The cut-off level of visual acuity should be 0.52 logMAR. With varied IOL designs, 3-piece C haptic IOL showed a smaller PCO area and thickness than the 1-piece 3 haptic IOL and 1-piece 4 haptic IOL. PCO area and thickness values for an IOL with a diameter ≤11.0 mm was greater than for an IOL with a diameter of 12.5 mm, and the differences were statistically significant. PCO area and thickness increased when IOL haptic angulation increased (from 0 to 12 degrees). CONCLUSION: In PCO eyes, cut-off level of visual acuity is 0.52 logMAR. With more severe PCO, visual acuity maybe not enough to describe the visual function impairment. PCO severity and IOL-PC space are significantly correlated with axial length and IOL design and material.

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Sha-Sha Yu, Cheng-Zhe Lu, Ya-Wen Guo, et al. Anterior segment OCT application in quantifying posterior capsule opacification severity with varied intraocular lens designs. Int J Ophthalmol, 2021,14(9):1384-1391

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Publication History
  • Received:January 21,2021
  • Revised:February 20,2021
  • Adopted:
  • Online: August 23,2021
  • Published: