Changes in Schlemm’s canal, trabecular meshwork, and relevant parameters in the early stage after SMILE of myopia patients
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Jun-Ming Wang. Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. eyedrwjm@163.com; Dan-Dan Yang. Department of Refractive Surgery, Wuhan EyeGood Ophthalmic Hospital, 403 Fazhan Avenue, Wuhan 430014, Hubei Province, China. 14727523@qq.com

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Supported by the National Natural Science Foundation of China (No.81974133).

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    Abstract:

    AIM: To observe the changes in Schlemm's canal (SC), trabecular meshwork (TM), and anterior chamber relevant parameters after small incision lenticule extraction (SMILE) of myopia patients. METHODS: A total of 58 eyes from 30 patients who underwent SMILE were divided into a low and moderate myopia group (group A, 32 eyes) and a high myopia group (group B, 26 eyes). The diameter and area of the SC, the width and thickness of TM obtained by CIRRUS HD-OCT5000, and the related anterior chamber parameters obtained by Pentacam anterior segment analysis system, accommodation amplitude (AMP) were observed pre- and postoperatively. The preoperative intraocular pressure (IOP) and postoperative correction of intraocular pressure (IOPcc) were measured. RESULTS: The diameter and area of the SC in the two groups were significantly increased postoperatively (all P<0.01). The TM width of the patients in the two groups were increased at 1mo after surgery (both P<0.01), but the TM thickness did not change (P>0.05). The corneal curvature, central anterior chamber depth, and anterior chamber volume decreased after SMILE surgery (all P<0.01). There was a weak negative correlation between the SC area change and AMP change in group A (r=-0.362, P<0.01). The postoperative IOP decreased after correction by Shah formula (P<0.05). CONCLUSION: SC and TM in myopia patients change in the early postoperative stage of SMILE and the IOP is decline.

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Dan-Dan Yang, Zhi-Qi Chen, Wei Chen, et al. Changes in Schlemm’s canal, trabecular meshwork, and relevant parameters in the early stage after SMILE of myopia patients. Int J Ophthalmol, 2022,15(2):291-298

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Publication History
  • Received:November 06,2020
  • Revised:May 27,2021
  • Adopted:
  • Online: January 26,2022
  • Published: