Regional chemotherapy for uveal melanoma liver metastases
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Wen-Bin Wei. Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. weiwenbin@mail.ccmu.edu.cn

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Supported by National Natural Science Foundation of China (No.82141128); The Capital Health Research and Development of Special (No.2020-1-2052); Beijing Natural Science Foundation (No.7204245); Science & Technology Project of Beijing Municipal Science & Technology Commission (No.Z201100005520045; No.Z181100001818003); Scientific Research Common Program of Beijing Municipal Commission of Education (No.KM202010025018); Beijing Municipal Administration of Hospitals’ Youth Programme (No.QML20190202); Beijing Dongcheng District Outstanding Talents Cultivating Plan (No.2018).

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    Abstract:

    Chemotherapy remains an important approach for the treatment of liver metastases from uveal melanoma (UM). Compared with systemic chemotherapy, regional chemotherapy has similar efficacy and fewer systemic adverse effects. Regional chemotherapy for UM liver metastases includes hepatic artery infusion (HAI), transarterial chemoembolization (TACE), and isolated hepatic perfusion (IHP). In this review, we aim to examine the efficacy of regional chemotherapy and compare HAI, TACE, and IHP in terms of overall survival (OS). The three approaches showed no obvious difference in OS results.

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Yang-Xu Tao, Hao-Wen Li, Jing-Ting Luo, et al. Regional chemotherapy for uveal melanoma liver metastases. Int J Ophthalmol, 2023,16(2):293-300

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Publication History
  • Received:November 04,2022
  • Revised:December 26,2022
  • Adopted:
  • Online: February 02,2023
  • Published: